Why Vaccine Research Needs IgA and IgM Alongside IgG
Antibody responses are often summarized by a single number: the amount of antigen-specific IgG in blood. That measurement is useful, but it cannot describe every layer of protection. Respiratory and intestinal pathogens encounter mucosal surfaces before reaching deeper tissues, while early immune responses involve antibodies with different structures and functions. Examining IgA and IgM...
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