Two important mechanisms used by antibody to kill targeted cells are Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC), and Complement Dependent Cytotoxicity (CDC). Reliable and high quality ADCC & CDC assays have assumed greater significance with the growing importance in medicine of bio-engineering antibodies and their role in combating cancers. By implementing strict QC standards, Creative Diagnostics can perform high quality assays for ADCC/CDC.

CDC is the mechanism by which antibodies lyse unwanted targets by triggering a series complement-related reactions. The CDC assay is used as a safety profiling measure by screening  candidate(s) to ensure the compound doesn't induce complement events and to look for other unexpected effects. Fresh blood that is less than four hours old is used in this assay as there are better responses/results utilizing fresher blood.