What causes ear pain. Ear pain can be a distressing and uncomfortable sensation that can be caused by a variety of factors. Understanding the possible causes of ear pain is important in order to seek appropriate treatment and relief. One of the most common causes of ear pain is an ear infection. This can occur in the outer ear (otitis externa), middle ear (otitis media), or inner ear (otitis interna). Infections can be caused by bacteria or viruses, and often result in inflammation, pain, and sometimes a build-up of fluid or pus in the ear. Ear infections can be particularly painful, especially if left untreated. Another common cause of ear pain is a build-up of earwax. Earwax is a natural substance produced by the ear to protect and lubricate the ear canal. However, when too much earwax accumulates, it can become impacted and cause pain and discomfort. In some cases, the earwax may need to be removed by a healthcare best sinus irrigation system professional to alleviate the pain. Injuries to the